In
548, when Hou Jing, formerly an
Eastern Wei general, rebelled against Emperor Wu and quickly put the capital
Jiankang under siege, Xiao Yi did not personally lead forces to aid Jiankang; rather, he sent his
heir apparent Xiao Fangdeng (蕭方等) and Wang Sengbian. They arrived in Jiankang's vicinity in spring
549, and accepted command, as did the generals of the other provincial forces, of the general Liu Zhongli (柳仲禮). However, Liu, after a battle in spring 549 where he was nearly killed, became hesitant to engage Hou's forces, and Hou was able to continue sieging the palace, where Emperor Wu's own forces had been forced to defend themselves. When the palace fell in summer 549, allowing Hou to take Emperor Wu and his
crown prince Xiao Gang hostage, and Hou subsequently forced Emperor Wu to issue an edict disbanding the provincial troops under Liu's command, Wang and Pei Zhigao (裴之高) suggested Liu to make one last stand against Hou, but Liu took no action, and the provincial forces, including Xiao Fangdeng's, largely returned to their home provinces, although Wang, along with Liu and several other generals, surrendered to Hou. Hou's strategist
Wang Wei suggested to Hou that Wang Sengbian should be detained, but Hou decided against it and allowed Wang Sengbian to return to Jingling. Once Wang Sengbian returned to Jingling, he again was under Xiao Yi's command.
Soon thereafter, Xiao Yi was in a dispute with his nephew Xiao Yu (蕭譽) the Prince of Hedong and governor of Xiang Province (湘州, modern
Hunan), who refused to follow his orders. Initially, he sent Xiao Fangdeng against Xiao Yu, but Xiao Fangdeng was defeated and killed in battle. He then ordered Wang Sengbian and Bao Quan (鮑泉) to attack Xiao Yu and further ordered them to leave immediately. Wang, who was then at Xiao Yi's headquarters in
Jiangling, wanted to wait for Jingling Commandery troops to arrive, and so he and Bao personally visited Xiao Yi to request a delay. Xiao Yi, suspecting Wang of not committing to his cause, rebuked Wang and unsheathed his sword, cutting Wang in the thigh and then imprisoning him. Wang's mother immediately visited Xiao Yi, crying and blaming herself for not disciplining her son correctly, asking for Xiao Yi's forgiveness. Xiao Yi calmed down and gave her medicine for healing wounds, and she used the medicine to help her son recover, but Xiao Yi still kept Wang imprisoned. Bao, in fear, did not persist in his request and left to attack Xiao Yu immediately.
In fall 549, with Bao putting Xiao Yu's headquarters at
Changsha under siege but unable to capture it, Xiao Yu's brother
Xiao Cha the Prince of Yueyang, trying to save his brother, attacked Jiangling from his headquarters at
Xiangyang. Xiao Yi, in fear, sent messengers to consult with Wang, still in prison, on how to deal with Xiao Cha. Wang made several suggestions, and Xiao Yi released him and made him the commander of Jiangling's defense forces. Wang was able to repel Xiao Cha's attacks, and when Xiao Cha's general Du An (杜岸) defected and attacked Xiangyang, Xiao Cha was forced to withdraw. Xiao Yi subsequently sent Wang to replace Bao as the commander against Xiao Yu, and Wang, when taking over command from Bao, was compelled to lock Bao in chains, despite his friendship with Bao, to avoid an appearance of disobeying Xiao Yi, although Xiao Yi later released Bao.
In summer
550, Changsha finally fell. Wang captured Xiao Yu and beheaded him, delivering his head to Xiao Yi, who subsequently returned the head to Changsha for burial. Wang took Xiao Yu's general Zhou Tiehu (周鐵虎) captive, and was about to execute Zhou, who had defeated Xiao Fangdeng, by boiling him to death. When Zhou yelled, "Hou Jing has not yet been destroyed. Why kill a brave soldier?" Wang was impressed by Zhou and released him, making him a key subordinate.
In fall 550, with Xiao Yi's older brother Xiao Guan (蕭綸) the Prince of Shaoyang reorganizing his forces at Jiangxia (江夏, in modern
Wuhan, Hubei) and planning to attack Hou, Xiao Yi was displeased because he saw Xiao Guan as a potential competitor for the throne. He therefore sent Wang and Bao toward Jiangxia, claiming to be merely welcoming Xiao Guan and making Xiao Guan the governor of Xiang Province. As Wang approached Jiangxia, Xiao Guan sent Wang a rebuke that stated, "You are a general who killed a man's nephew previously for him, and now you are killing his brother for him. If you use these methods to gain power, you will be rejected by the people." Wang forwarded the letter to Xiao Yi, who ordered him to launch an attack on Xiao Guan. Xiao Guan, instead of engaging him, abandoned Jiangxia and fled. Wang took Ying Province (郢州, modern eastern Hubei).
In summer
551, Xiao Yi commissioned Wang with a substantial force to have him attack Hou. After Wang departed from Jiangling, however, news was received that Hou's forces under the general Ren Yue (任約) had captured Jiangxia, and Ren and Hou were approaching Jiangling. Wang stopped at Baling (巴陵, in modern
Yueyang, Hunan) and fortified it against a possible Hou attack. When Hou arrived, he put Baling under siege, and Wang each time repelled Hou, who became impressed at his bravery. Eventually, Hou's food supplies ran out, and Ren was captured, forcing Hou to flee. Wang advanced to Jiangxia, putting it under siege. When Hou's general Song Zixian (宋子仙), whom Hou left in charge at Jiangxia, offered to surrender the city with the condition that Wang allowed him to retreat, Wang agreed and prepared ships for Song, but as soon as Song left the city, Wang attacked and captured him and Ding He (丁和), who were delivered to Jiangling and executed.
Wang continued to advance east, and in fall 551, he joined forces with
Chen Baxian, who had advanced north from Guang Province (廣州, modern
Guangdong). Wang and Chen, by Xiao Yi's orders, stopped at Xunyang (尋陽, in modern
Jiujiang, Jiangxi) to wait for the rest of the troops. Xiao Yi also made Wang the governor of Jiang Province. When Wang heard the news that Hou had killed Xiao Gang, who had succeeded Emperor Wu after Emperor Wu's death in summer 549 (as Emperor Jianwen), he submitted a petition to Xiao Yi, asking Xiao Yi to take the throne, but Xiao Yi did not accept it. (In winter 551, Hou further deposed Emperor Wu's great-grandson
Xiao Dong and declared himself the Emperor of Han.)
In spring
552, by Xiao Yi's orders, Wang and Chen continued east against Hou. Before they left Xunyang, they built an altar at which they swore allegiance to Liang. They quickly advanced on Jiankang, defeating Hou's general Hou Zijian (侯子鑒). When Hou Jing himself attacked them, they defeated him, and he fled. They entered Jiankang. Records indicate that Wang's forces were lacking in mlitary discipline, and they pillaged the people of Jiankang, stripping them of wealth and clothes. Further, soldiers set the Taiji Palace (太極殿) ablaze -- although Wang blamed this incident on
Wang Lin, leading to Xiao Yi eventually putting Wang Lin under arrest. He sent the general Hou Tian (侯瑱) to pursue Hou Jing, while burying Emperor Jianwen with proper ceremony. He requested again that Xiao Yi return to Jiankang to take the throne, but Xiao Yi again declined, effectively putting Wang in charge of the eastern empire, and Wang in turn put Chen in charge of the important city Jingkou (京口, in modern
Zhenjiang, Jiangsu). Soon, Hou Jing, in flight, was killed by his own guards, and his body was delivered to Jiankang. Wang delivered Hou's head to Jiangling and delivered his hands to Eastern Wei's successor state
Northern Qi. Xiao Yi created Wang the Duke of Changning. In light of Hou's defeat, Northern Qi seized nearly all of the formerly Liang territory north of the
Yangtze River, and Wang and Chen had to fend themselves against Northern Qi attacks. Once they did, however, Wang, not wanting to aggravate Northern Qi, did not counterattack, and further, when the provincial gentry from those lost provinces requested that he attack because they did not want to be under Northern Qi rule, he rejected their requests, although when the people of Guangling (廣陵, in modern
Yangzhou, Jiangsu) claimed to be ready to rise against Northern Qi, he permitted Chen to advance to Guangling, putting it under siege. Subsequently, Northern Qi agreed to return Guangling and Liyang (歷陽, in modern
Chaohu, Anhui), and the campaign ended.