Applegate quit school at age 17 to pursue acting. From 1987 to 1997, she played Kelly Bundy on
Married… with Children. From 1998 to 2000, she starred in her own sitcom,
Jesse, on
NBC. In 2002 she co-starred with
Cameron Diaz, on the comic movie
The Sweetest Thing, playing the role of Courtney Rockcliffe, Diaz's best friend.
At the tender age of three months old, Christina Applegate made her TV debut appearing with her mother in the soap
Days of Our Lives and later, at age five months, was seen in a commercial for
Playtex.
Christina landed on the big screen at age nine when she was seen in the 1981 films
Jaws of Satan (a.k.a. King Cobra) and
Beatlemania.
Applegate debuted in a television movie as Young Grace Kelly in the biopic
Grace Kelly (1983, opposite
Cheryl Ladd) and appeared on her first TV series in Showtime's political comedy
Washingtoon (1985), in which she played a Congressman's daughter. She was also spotted as a guest in the shows
Father Murphy (1981) and
Charles in Charge (1984 and 1985).
In 1986, Applegate won the role of Robin Kennedy (1986-1987), a cop's daughter, on the police drama series
Heart of the City. Meanwhile, she was also seen guest starring in the sitcoms
All is Forgiven,
Still the Beaver,
Amazing Stories, and
Family Ties.
Applegate eventually scored her most memorable role of ditzy Kelly Bundy in Fox's comedy series
Married... with Children. She portrayed her character for ten years (1987-1997) in the successful sitcom. While working on the series, Applegate was seen in
Dance 'Til Dawn (1988, NBC) and in
Streets (1990).
Applegate guest starred in
21 Jump Street (1988),
Top of the Heap (1991, as Kelly Bundy) as well as hosted
Saturday Night Live (May 1993) and
Mad TV (1996).
Playing Sue Ellen Crandell in the comedy feature
Don't Tell Mom the Babysitter's Dead (1991) was Applegate's first starring role. She followed it up with films like
Vibrations (1995),
Across the Moon (1995),
Wild Bill (1995) and
Mars Attacks! (1996) as well as
Nowhere (1997).
After the sitcom
Married... with Children was canceled in May 1997, Applegate starred as Claudine Van Doozen in the independent feature
Claudine's Return (a.k.a. Kiss of Fire), was cast in the action-comedy
The Big Hit, and played the fiancée of a Mob descendant in the Mafia satire
Jane Austen's Mafia (1998).
In that same year, NBC handed her the leading part of "Jesse" in their
sitcom with the same title. The series debuted in 1998, received rave reviews, and brought Applegate a
People's Choice Award for Favorite Female Performer in a New TV series and the TV Guide Award for Star of a New Series as well as a nomination at the
Golden Globe for Lead Actress in a Comedy. Though the series gained praise, it only stayed on for two years and eventually was canceled in 2000.
"This was a major commitment. I really had to sit and think about it. I eventually came to the conclusion that it came into my life for a reason." Christina Applegate (on accepting her role in the sitcom Jesse).
The new millennium saw Applegate playing the dual role of a 12th-century noblewoman, Princess Rosalind, and her 21st-century descendant, Julia Malfete, in the time-travel comedy
Just Visiting (2001). After gaining wide notice for playing
Cameron Diaz's levelheaded best friend, Courtney Rockcliffe, in
The Sweetest Thing (2002), Applegate continued to win roles in such movies as
Heroes (2002), the airplane comedy
View from the Top (2003),
Wonderland (2003),
Grand Theft Parsons (2003),
Surviving Christmas (2004) and
Employee of the Month (2004). Behind the screen, she was the executive producer of
Comforters, Miserable (2001).
As for her small screen work, Applegate won the 55th Annual Prime Time Emmy Award for Best Guest Actress in a Comedy after she guest starred as Amy Green,
Jennifer Aniston's sister, in the hit series
Friends in November 2002 and October 2003. On the silver screen, she portrayed TV anchorwoman Veronica Corningstone in the 2004 films
Anchorman: The Legend of Ron Burgundy and
Wake Up, Ron Burgundy: The Lost Movie.
Adding to her screen work, Applegate has performed on stage in such productions as
The Axeman's Jazz,
Nobody Leaves Empty Handed,
The Runthrough, as well as John Cassavetes'
The Third Day. (co-starring Gena Rowlands). In 2004, she debuted on the Broadway stage playing the title role of Charity Hope Valentine in a revival of the 1966 musical
Sweet Charity. She eventually took home the 2005 Theatre World Award and was nominated for a 2005 Tony Award for Best Actress in a Musical.
Applegate was one of the founding members of the
Pussycat Dolls, which debuted at the
Viper Room on
Sunset Strip,
Los Angeles in 1995.
Applegate emceed for the Dolls when they moved to
The Roxy in 2002.
While playing the title role in a revival of
Sweet Charity, she broke her foot, and it was announced that the musical would close during previews. She persuaded the producers to rescind their decision, and on
April 18 2005, she made her
Broadway debut.
Sweet Charity ended its Broadway run on
December 31, 2005. She also guest-starred on two episodes of
Friends, one in the ninth season, and one in the tenth, titled "
The One with Rachel's Other Sister" and "
The One Where Rachel's Sister Babysits" respectively (in 2002 and 2003) as Amy Green,
Rachel's (
Jennifer Aniston) youngest sister. She won an Emmy for her performance in "The One with Rachel's Other Sister". In 2006, she appeared in an advertising campaign for
Hanes title
"Look who we've got our Hanes on now". The campaign started in 2005 but she,
Jennifer Love Hewitt, and
Kevin Bacon were added to the ads in 2006.
In 2006, Applegate appeared in
Jessica Simpson's music video "
A Public Affair", alongside
Eva Longoria,
Ryan Seacrest and
Christina Milian.
Christina is currently starring in the
ABC comedy,
Samantha Who?.
Jean Smart,
Jennifer Esposito, and
Melissa McCarthy are co-starring. The series is about a 30-year-old who, after a hit-and-run accident, develops amnesia and has to rediscover her life, her relationships and herself.