He wrote in
Ancient Greek the grammar handbooks "Summarized Questions of the Eight Parts of Word After Their Rules" (Ερωτήματα Συνοπτικά Τον Οκτώ Του Λόγου Μερών Μετά Τινών Κανόνων). He translated
Galen's Anatomy into Latin.
As a scholar, Chalcondyles published the
editio princeps of Homer, ('Ομήρου τα Σωζόμενα', Florence, 1488),
Isocrates, (Milan, 1493) and the
Suda (Σούδα), the
Byzantine lexicon (1494).
*Greek Grammar, edited 1546 by
Melchior Volmar in
Basel
*Latin translation of the
Anatomical Procedures of
Galen, edited and published in 1529 by
Jacopo Berengario da Carpi
*1488,
editio princeps of Homer's
Ilias and
Odyssey,
Poiesis Hapasa, edited by
Bernardus Nerlius and Demetrius Chalcondylas, appeared in Florence, not before 13 January 1489, in two folio volumes. It was the first Greek book to be printed in Florence. The Greek type used to print the 1488-89 Homer is believed to have been cast by the
Cretan Demetrius Damilas from the type that he had used to print
Constantinus Lascaris’ Erotemata (Milan, 1476), the first book to be printed entirely in Greek, based upon the hand of Damilas’s fellow scribe
Michael Apostolis.