Galifianakis got his start on television in 1996, when he played the recurring role of a stoner named Bobby in the short-lived sitcom,
Boston Common. In 2001, Galifianakis co-starred in the
film Out Cold. He has had small roles in
Corky Romano,
Below,
Bubble Boy and
Heartbreakers, and has parts in
Visioneers and
Into the Wild, which are to be released in 2007.
In 2002, he was the host of his own talk show, called
Late World with Zach. His next television role was as a coroner named
Davis in the
FOX drama
Tru Calling, which lasted from
2003 to
2005. He has also appeared many times on
Jimmy Kimmel Live and has made three appearances on
Reno 911! as "Frisbee".
Galifianakis starred as Alan Finger on the
Comedy Central show
Dog Bites Man, a fake news program that caught people during candid moments as they acted under the impression that they are being interviewed by a real news crew. In addition, he was on an episode of the
Comedy Central show,
The Sarah Silverman Program, as Fred the Homeless Guy. He also had a recurring guest role as a doctor on the animated
Adult Swim show
Tom Goes to the Mayor and appeared in the new show
Tim and Eric Awesome Show, Great Job! in the "Gravy Robbers" sketches as deranged mentor Tairy Greene.
In 2006, Galifianakis was featured in
Fiona Apple's music video for the song, "Not About Love". In the video, he is seen
lip synching the lyrics to the song. In June 2006 Galifianakis released the single "
Come Over and Get It (Up in 'Dem Guts)", a comedic rap/hip-hop/dance song which features Apple's vocals. More recently, Galifianakis performed on a tour called the "
Comedians of Comedy" with
Brian Posehn, Patton Oswalt, and
Maria Bamford. They chose to perform at live rock clubs as opposed to comedy clubs to try to reach a different audience. Much of the tour was taped, and has been featured in both a short-lived TV series on Comedy Central and a full length movie that has appeared at
SXSW and on
Showtime. A DVD featuring Galifianakis's work,
Live at the Purple Onion, was released on March 6th, 2007.
Galifianakis divides his time between two residences, one in Venice Beach, CA, and the other in the foothills of North Carolina, the latter of which is a 60-acre farm that he hopes to turn into a "writer's retreat". It was on this farm that he filmed the music video for
Kanye West's song, "
Can't Tell Me Nothing".